Mechanistic Insights into Two-Phase Radical C–H Arylations

[Image: see text] Kinetic, spectroscopic, and computational studies of radical C–H arylations highlight the interplay between chemical and physical rate processes in these multiphase reactions. Anomalous concentration dependences observed here may be reconciled by considering the role of phase trans...

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Autores principales: Baxter, Ryan D., Liang, Yong, Hong, Xin, Brown, Timothy A., Zare, Richard N., Houk, K. N., Baran, Phil S., Blackmond, Donna G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4665085/
https://www.ncbi.nlm.nih.gov/pubmed/26640819
http://dx.doi.org/10.1021/acscentsci.5b00332
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author Baxter, Ryan D.
Liang, Yong
Hong, Xin
Brown, Timothy A.
Zare, Richard N.
Houk, K. N.
Baran, Phil S.
Blackmond, Donna G.
author_facet Baxter, Ryan D.
Liang, Yong
Hong, Xin
Brown, Timothy A.
Zare, Richard N.
Houk, K. N.
Baran, Phil S.
Blackmond, Donna G.
author_sort Baxter, Ryan D.
collection PubMed
description [Image: see text] Kinetic, spectroscopic, and computational studies of radical C–H arylations highlight the interplay between chemical and physical rate processes in these multiphase reactions. Anomalous concentration dependences observed here may be reconciled by considering the role of phase transfer processes that mediate concentrations in each phase. In addition, understanding interactions through phase boundaries enables their use in optimization of reaction performance.
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spelling pubmed-46650852015-12-04 Mechanistic Insights into Two-Phase Radical C–H Arylations Baxter, Ryan D. Liang, Yong Hong, Xin Brown, Timothy A. Zare, Richard N. Houk, K. N. Baran, Phil S. Blackmond, Donna G. ACS Cent Sci [Image: see text] Kinetic, spectroscopic, and computational studies of radical C–H arylations highlight the interplay between chemical and physical rate processes in these multiphase reactions. Anomalous concentration dependences observed here may be reconciled by considering the role of phase transfer processes that mediate concentrations in each phase. In addition, understanding interactions through phase boundaries enables their use in optimization of reaction performance. American Chemical Society 2015-11-02 2015-11-25 /pmc/articles/PMC4665085/ /pubmed/26640819 http://dx.doi.org/10.1021/acscentsci.5b00332 Text en Copyright © 2015 American Chemical Society This is an open access article published under an ACS AuthorChoice License (http://pubs.acs.org/page/policy/authorchoice_termsofuse.html) , which permits copying and redistribution of the article or any adaptations for non-commercial purposes.
spellingShingle Baxter, Ryan D.
Liang, Yong
Hong, Xin
Brown, Timothy A.
Zare, Richard N.
Houk, K. N.
Baran, Phil S.
Blackmond, Donna G.
Mechanistic Insights into Two-Phase Radical C–H Arylations
title Mechanistic Insights into Two-Phase Radical C–H Arylations
title_full Mechanistic Insights into Two-Phase Radical C–H Arylations
title_fullStr Mechanistic Insights into Two-Phase Radical C–H Arylations
title_full_unstemmed Mechanistic Insights into Two-Phase Radical C–H Arylations
title_short Mechanistic Insights into Two-Phase Radical C–H Arylations
title_sort mechanistic insights into two-phase radical c–h arylations
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4665085/
https://www.ncbi.nlm.nih.gov/pubmed/26640819
http://dx.doi.org/10.1021/acscentsci.5b00332
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