Cargando…

Increased activity of CHK enhances the radioresistance of MCF-7 breast cancer stem cells

The resistance of breast cancer to radiotherapy remains a major obstacle to successful cancer management. Radiotherapy may result in DNA damage and activate breast cancer stem cells. DNA damage may lead to activation of the checkpoint kinase (CHK) signaling pathway, of which debromohymenialdisine (D...

Descripción completa

Detalles Bibliográficos
Autores principales:	YANG, ZHI-XUE, SUN, YI-HUI, HE, JIAN-GANG, CAO, HUA, JIANG, GUO-QIN
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2015
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4665200/ https://www.ncbi.nlm.nih.gov/pubmed/26788148 http://dx.doi.org/10.3892/ol.2015.3777

Ejemplares similares

Bmi-1 induces radioresistance in MCF-7 mammary carcinoma cells
por: LIU, ZHI-GANG, et al.
Publicado: (2011)

Enhanced radiation response in radioresistant MCF-7 cells by targeting peroxiredoxin II
por: Diaz, Anthony Joseph Gomez, et al.
Publicado: (2013)

Targeting radioresistant breast cancer cells by single agent CHK1 inhibitor via enhancing replication stress
por: Zhang, Yao, et al.
Publicado: (2016)

Profiling Global Kinome Signatures of the Radioresistant MCF-7/C6 Breast Cancer Cells Using MRM-based Targeted Proteomics
por: Guo, Lei, et al.
Publicado: (2014)

Kinase-independent role for CRAF-driving tumour radioresistance via CHK2
por: Advani, Sunil J., et al.
Publicado: (2015)

UBE2T-regulated H2AX monoubiquitination induces hepatocellular carcinoma radioresistance by facilitating CHK1 activation
por: Sun, Jingyuan, et al.
Publicado: (2020)

ATM-mediated stabilization of ZEB1 promotes DNA damage response and radioresistance through CHK1
por: Zhang, Peijing, et al.
Publicado: (2014)

SALL4 induces radioresistance in nasopharyngeal carcinoma via the ATM/Chk2/p53 pathway
por: Nie, Xin, et al.
Publicado: (2019)

Sirt3 Promoted DNA Damage Repair and Radioresistance Through ATM-Chk2 in Non-small Cell Lung Cancer Cells
por: Cao, Kun, et al.
Publicado: (2021)

Long noncoding RNA LINC02582 acts downstream of miR-200c to promote radioresistance through CHK1 in breast cancer cells
por: Wang, Baiyao, et al.
Publicado: (2019)

Increased Notch Signaling Enhances Radioresistance of Malignant Stromal Cells Induced by Glioma Stem/ Progenitor Cells
por: Shen, Yuntian, et al.
Publicado: (2015)

Cytotoxic and chemomodulatory effects of Phyllanthus niruri in MCF-7 and MCF-7(ADR) breast cancer cells
por: Abdel-Sattar, Ola E., et al.
Publicado: (2023)

Chk1, Chk2, is the amplifier on?
por: Dove, Alan W.
Publicado: (2001)

Gold nanoparticle uptake is enhanced by estradiol in MCF-7 breast cancer cells
por: Lara-Cruz, Carlos, et al.
Publicado: (2019)

The role of a new CD44st in increasing the invasion capability of the human breast cancer cell line MCF-7
por: Fang, Xin Jian, et al.
Publicado: (2011)

Adipose-Derived Stem Cell Features and MCF-7
por: Garroni, Giuseppe, et al.
Publicado: (2021)

Reduced RKIP enhances nasopharyngeal carcinoma radioresistance by increasing ERK and AKT activity
por: Yuan, Li, et al.
Publicado: (2016)

Gambogic Acid Lysinate Induces Apoptosis in Breast Cancer MCF-7 Cells by Increasing Reactive Oxygen Species
por: Zhen, Yong-Zhan, et al.
Publicado: (2015)

Mechanism of EGCG promoting apoptosis of MCF-7 cell line in human breast cancer
por: Huang, Chao-You, et al.
Publicado: (2017)

Anticancer effects of liriodenine on the cell growth and apoptosis of human breast cancer MCF-7 cells through the upregulation of p53 expression
por: Li, Zhi-Hua, et al.
Publicado: (2017)

Differentially expressed gene profile and relevant pathways of the traditional Chinese medicine cinobufotalin on MCF-7 breast cancer cells
por: Li, Jie, et al.
Publicado: (2019)

Aberrant N-glycolylneuraminic acid in breast MCF-7 cancer cells and cancer stem cells
por: Yang, Wenqian, et al.
Publicado: (2022)

Impairment of Glucose Metabolism and Suppression of Stemness in MCF-7/SC Human Breast Cancer Stem Cells by Nootkatone
por: Nguyen, Yen Thi-Kim, et al.
Publicado: (2022)

Chronic Oxidative Stress Increases Growth and Tumorigenic Potential of MCF-7 Breast Cancer Cells
por: Mahalingaiah, Prathap Kumar S., et al.
Publicado: (2014)

The Chk1 inhibitor MK-8776 increases the radiosensitivity of human triple-negative breast cancer by inhibiting autophagy
por: Zhou, Zhi-rui, et al.
Publicado: (2017)

BRD7 suppresses tumor chemosensitivity to CHK1 inhibitors by inhibiting USP1-mediated deubiquitination of CHK1
por: Li, Lemin, et al.
Publicado: (2023)

A Novel Electrochemical Differentiation between Exosomal-RNA of Breast Cancer MCF7 and MCF7/ADR-Resistant Cells
por: Abdelaziz, Mohammed H., et al.
Publicado: (2023)

MiR-7-5p/KLF4 signaling inhibits stemness and radioresistance in colorectal cancer
por: Shang, Yuanyuan, et al.
Publicado: (2023)

Silibinin Enhances Ultraviolet B-Induced Apoptosis in MCF-7 Human Breast Cancer Cells
por: Noh, Eun-Mi, et al.
Publicado: (2011)

A Novel Agent Enhances the Chemotherapeutic Efficacy of Doxorubicin in MCF-7 Breast Cancer Cells
por: Wang, Liang, et al.
Publicado: (2016)

Dicoma anomala Enhances Phthalocyanine Mediated Photodynamic Therapy in MCF-7 Breast Cancer Cells
por: Chota, Alexander, et al.
Publicado: (2022)

Cytotoxicity Enhancement in MCF-7 Breast Cancer Cells with Depolymerized Chitosan Delivery of α-Mangostin
por: Herdiana, Yedi, et al.
Publicado: (2022)

Conjugation of Hypericin to Gold Nanoparticles for Enhancement of Photodynamic Therapy in MCF-7 Breast Cancer Cells
por: Mokoena, Dimakatso, et al.
Publicado: (2022)

Connexin46 Expression Enhances Cancer Stem Cell and Epithelial-to-Mesenchymal Transition Characteristics of Human Breast Cancer MCF-7 Cells
por: Acuña, Rodrigo A., et al.
Publicado: (2021)

Divergence of Intracellular Trafficking of Sphingosine Kinase 1 and Sphingosine-1-Phosphate Receptor 3 in MCF-7 Breast Cancer Cells and MCF-7-Derived Stem Cell-Enriched Mammospheres
por: Sukocheva, Olga A., et al.
Publicado: (2021)

The Effect of Cholesterol in MCF7 Human Breast Cancer Cells
por: Albi, Elisabetta, et al.
Publicado: (2023)

Evaluation of the Anticancer Activity of Calcium Ions Introduced into Human Breast Adenocarcinoma Cells MCF-7/WT and MCF-7/DOX by Electroporation
por: Bieżuńska-Kusiak, Katarzyna, et al.
Publicado: (2023)

Correction: Chronic Oxidative Stress Increases Growth and Tumorigenic Potential of MCF-7 Breast Cancer Cells
Publicado: (2014)

Increased Transfection of the Easily Oxidizable GC-Rich DNA Fragments into the MCF7 Breast Cancer Cell
por: Kostyuk, Svetlana V., et al.
Publicado: (2019)

ALG3 contributes to stemness and radioresistance through regulating glycosylation of TGF-β receptor II in breast cancer
por: Sun, Xiaoqing, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_j89iohhbp20c08298ri1bic7b7