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Increased activity of CHK enhances the radioresistance of MCF-7 breast cancer stem cells

The resistance of breast cancer to radiotherapy remains a major obstacle to successful cancer management. Radiotherapy may result in DNA damage and activate breast cancer stem cells. DNA damage may lead to activation of the checkpoint kinase (CHK) signaling pathway, of which debromohymenialdisine (D...

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Detalles Bibliográficos
Autores principales:	YANG, ZHI-XUE, SUN, YI-HUI, HE, JIAN-GANG, CAO, HUA, JIANG, GUO-QIN
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2015
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4665200/ https://www.ncbi.nlm.nih.gov/pubmed/26788148 http://dx.doi.org/10.3892/ol.2015.3777

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