Clinical metagenomic identification of Balamuthia mandrillaris encephalitis and assembly of the draft genome: the continuing case for reference genome sequencing

BACKGROUND: Primary amoebic meningoencephalitis (PAM) is a rare, often lethal, cause of encephalitis, for which early diagnosis and prompt initiation of combination antimicrobials may improve clinical outcomes. METHODS: In this study, we sequenced a full draft assembly of the Balamuthia mandrillaris...

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Detalles Bibliográficos
Autores principales: Greninger, Alexander L., Messacar, Kevin, Dunnebacke, Thelma, Naccache, Samia N., Federman, Scot, Bouquet, Jerome, Mirsky, David, Nomura, Yosuke, Yagi, Shigeo, Glaser, Carol, Vollmer, Michael, Press, Craig A., Klenschmidt-DeMasters, Bette K., Dominguez, Samuel R., Chiu, Charles Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4665321/
https://www.ncbi.nlm.nih.gov/pubmed/26620704
http://dx.doi.org/10.1186/s13073-015-0235-2

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