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Low expression of spindle checkpoint protein, Cenp-E, causes numerical chromosomal abnormalities in HepG-2 human hepatoma cells

The aim of the present study was to investigate the expression, localization and role of centromere-associated protein E (Cenp-E) in hepatoma cells. The Cenp-E mRNA expression levels in the HepG-2 human hepatocellular carcinoma and LO2 normal hepatic cell lines following treatment with nocodazole we...

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Detalles Bibliográficos
Autores principales: LIU, BIN, LUO, HONGMEI, WU, GUANG, LIU, JING, PAN, JIE, LIU, ZHUORAN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4665365/
https://www.ncbi.nlm.nih.gov/pubmed/26722229
http://dx.doi.org/10.3892/ol.2015.3721