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Drinking Hydrogen-Rich Water Has Additive Effects on Non-Surgical Periodontal Treatment of Improving Periodontitis: A Pilot Study

Oxidative stress is involved in the pathogenesis of periodontitis. A reduction of oxidative stress by drinking hydrogen-rich water (HW) might be beneficial to periodontal health. In this pilot study, we compared the effects of non-surgical periodontal treatment with or without drinking HW on periodo...

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Autores principales: Azuma, Tetsuji, Yamane, Mayu, Ekuni, Daisuke, Kawabata, Yuya, Kataoka, Kota, Kasuyama, Kenta, Maruyama, Takayuki, Tomofuji, Takaaki, Morita, Manabu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4665424/
https://www.ncbi.nlm.nih.gov/pubmed/26783840
http://dx.doi.org/10.3390/antiox4030513
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author Azuma, Tetsuji
Yamane, Mayu
Ekuni, Daisuke
Kawabata, Yuya
Kataoka, Kota
Kasuyama, Kenta
Maruyama, Takayuki
Tomofuji, Takaaki
Morita, Manabu
author_facet Azuma, Tetsuji
Yamane, Mayu
Ekuni, Daisuke
Kawabata, Yuya
Kataoka, Kota
Kasuyama, Kenta
Maruyama, Takayuki
Tomofuji, Takaaki
Morita, Manabu
author_sort Azuma, Tetsuji
collection PubMed
description Oxidative stress is involved in the pathogenesis of periodontitis. A reduction of oxidative stress by drinking hydrogen-rich water (HW) might be beneficial to periodontal health. In this pilot study, we compared the effects of non-surgical periodontal treatment with or without drinking HW on periodontitis. Thirteen patients (3 women, 10 men) with periodontitis were divided into two groups: The control group (n = 6) or the HW group (n = 7). In the HW group, participants consumed HW 4–5 times/day for eight weeks. At two to four weeks, all participants received non-surgical periodontal treatment. Oral examinations were performed at baseline, two, four and eight weeks, and serum was obtained at these time points to evaluate oxidative stress. At baseline, there were no significant differences in periodontal status between the control and HW groups. The HW group showed greater improvements in probing pocket depth and clinical attachment level than the control group at two, four and eight weeks (p < 0.05). The HW group also exhibited an increased serum level of total antioxidant capacity at four weeks, compared to baseline (p < 0.05). Drinking HW enhanced the effects of non-surgical periodontal treatment, thus improving periodontitis.
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spelling pubmed-46654242016-01-14 Drinking Hydrogen-Rich Water Has Additive Effects on Non-Surgical Periodontal Treatment of Improving Periodontitis: A Pilot Study Azuma, Tetsuji Yamane, Mayu Ekuni, Daisuke Kawabata, Yuya Kataoka, Kota Kasuyama, Kenta Maruyama, Takayuki Tomofuji, Takaaki Morita, Manabu Antioxidants (Basel) Article Oxidative stress is involved in the pathogenesis of periodontitis. A reduction of oxidative stress by drinking hydrogen-rich water (HW) might be beneficial to periodontal health. In this pilot study, we compared the effects of non-surgical periodontal treatment with or without drinking HW on periodontitis. Thirteen patients (3 women, 10 men) with periodontitis were divided into two groups: The control group (n = 6) or the HW group (n = 7). In the HW group, participants consumed HW 4–5 times/day for eight weeks. At two to four weeks, all participants received non-surgical periodontal treatment. Oral examinations were performed at baseline, two, four and eight weeks, and serum was obtained at these time points to evaluate oxidative stress. At baseline, there were no significant differences in periodontal status between the control and HW groups. The HW group showed greater improvements in probing pocket depth and clinical attachment level than the control group at two, four and eight weeks (p < 0.05). The HW group also exhibited an increased serum level of total antioxidant capacity at four weeks, compared to baseline (p < 0.05). Drinking HW enhanced the effects of non-surgical periodontal treatment, thus improving periodontitis. MDPI 2015-07-09 /pmc/articles/PMC4665424/ /pubmed/26783840 http://dx.doi.org/10.3390/antiox4030513 Text en © 2015 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Azuma, Tetsuji
Yamane, Mayu
Ekuni, Daisuke
Kawabata, Yuya
Kataoka, Kota
Kasuyama, Kenta
Maruyama, Takayuki
Tomofuji, Takaaki
Morita, Manabu
Drinking Hydrogen-Rich Water Has Additive Effects on Non-Surgical Periodontal Treatment of Improving Periodontitis: A Pilot Study
title Drinking Hydrogen-Rich Water Has Additive Effects on Non-Surgical Periodontal Treatment of Improving Periodontitis: A Pilot Study
title_full Drinking Hydrogen-Rich Water Has Additive Effects on Non-Surgical Periodontal Treatment of Improving Periodontitis: A Pilot Study
title_fullStr Drinking Hydrogen-Rich Water Has Additive Effects on Non-Surgical Periodontal Treatment of Improving Periodontitis: A Pilot Study
title_full_unstemmed Drinking Hydrogen-Rich Water Has Additive Effects on Non-Surgical Periodontal Treatment of Improving Periodontitis: A Pilot Study
title_short Drinking Hydrogen-Rich Water Has Additive Effects on Non-Surgical Periodontal Treatment of Improving Periodontitis: A Pilot Study
title_sort drinking hydrogen-rich water has additive effects on non-surgical periodontal treatment of improving periodontitis: a pilot study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4665424/
https://www.ncbi.nlm.nih.gov/pubmed/26783840
http://dx.doi.org/10.3390/antiox4030513
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