A Review of the Use of Topical Calendula in the Prevention and Treatment of Radiotherapy-Induced Skin Reactions

Calendula is a topical agent derived from a plant of the marigold family Calendula Officinalis. Containing numerous polyphenolic antioxidants, calendula has been studied in both the laboratory and clinical setting for the use in treating and preventing radiation induced skin toxicity. Despite strong...

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Detalles Bibliográficos
Autores principales: Kodiyan, Joyson, Amber, Kyle T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4665477/
https://www.ncbi.nlm.nih.gov/pubmed/26783706
http://dx.doi.org/10.3390/antiox4020293
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author Kodiyan, Joyson
Amber, Kyle T.
author_facet Kodiyan, Joyson
Amber, Kyle T.
author_sort Kodiyan, Joyson
collection PubMed
description Calendula is a topical agent derived from a plant of the marigold family Calendula Officinalis. Containing numerous polyphenolic antioxidants, calendula has been studied in both the laboratory and clinical setting for the use in treating and preventing radiation induced skin toxicity. Despite strong evidence in the laboratory supporting calendula’s mechanism of action in preventing radiation induced skin toxicity, clinical studies have demonstrated mixed results. In light of the controversy surrounding the efficacy of calendula in treating and preventing radiodermatitis, the topic warrants further discussion.
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spelling pubmed-46654772016-01-14 A Review of the Use of Topical Calendula in the Prevention and Treatment of Radiotherapy-Induced Skin Reactions Kodiyan, Joyson Amber, Kyle T. Antioxidants (Basel) Review Calendula is a topical agent derived from a plant of the marigold family Calendula Officinalis. Containing numerous polyphenolic antioxidants, calendula has been studied in both the laboratory and clinical setting for the use in treating and preventing radiation induced skin toxicity. Despite strong evidence in the laboratory supporting calendula’s mechanism of action in preventing radiation induced skin toxicity, clinical studies have demonstrated mixed results. In light of the controversy surrounding the efficacy of calendula in treating and preventing radiodermatitis, the topic warrants further discussion. MDPI 2015-04-23 /pmc/articles/PMC4665477/ /pubmed/26783706 http://dx.doi.org/10.3390/antiox4020293 Text en © 2015 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Kodiyan, Joyson
Amber, Kyle T.
A Review of the Use of Topical Calendula in the Prevention and Treatment of Radiotherapy-Induced Skin Reactions
title A Review of the Use of Topical Calendula in the Prevention and Treatment of Radiotherapy-Induced Skin Reactions
title_full A Review of the Use of Topical Calendula in the Prevention and Treatment of Radiotherapy-Induced Skin Reactions
title_fullStr A Review of the Use of Topical Calendula in the Prevention and Treatment of Radiotherapy-Induced Skin Reactions
title_full_unstemmed A Review of the Use of Topical Calendula in the Prevention and Treatment of Radiotherapy-Induced Skin Reactions
title_short A Review of the Use of Topical Calendula in the Prevention and Treatment of Radiotherapy-Induced Skin Reactions
title_sort review of the use of topical calendula in the prevention and treatment of radiotherapy-induced skin reactions
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4665477/
https://www.ncbi.nlm.nih.gov/pubmed/26783706
http://dx.doi.org/10.3390/antiox4020293
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