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Oxidative Stress Is Associated with Neuroinflammation in Animal Models of HIV-1 Tat Neurotoxicity

HIV-1 trans-acting protein Tat, an essential protein for viral replication, is a key mediator of neurotoxicity. If Tat oxidant injury and neurotoxicity have been described, consequent neuroinflammation is less understood. Rat caudate-putamens (CPs) were challenged with Tat, with or without prior rSV...

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Detalles Bibliográficos
Autores principales:	Louboutin, Jean-Pierre, Agrawal, Lokesh, Reyes, Beverly A. S., Van Bockstaele, Elisabeth J., Strayer, David S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4665482/ https://www.ncbi.nlm.nih.gov/pubmed/26784879 http://dx.doi.org/10.3390/antiox3020414

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