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A Cystine-Rich Whey Supplement (Immunocal(®)) Delays Disease Onset and Prevents Spinal Cord Glutathione Depletion in the hSOD1(G93A) Mouse Model of Amyotrophic Lateral Sclerosis
Depletion of the endogenous antioxidant, glutathione (GSH), underlies progression of the devastating neurodegenerative disease, amyotrophic lateral sclerosis (ALS). Thus, strategies aimed at elevating GSH may yield new therapeutics for ALS. Here, we investigated the effects of a unique non-denatured...
Autores principales: | Ross, Erika K., Winter, Aimee N., Wilkins, Heather M., Sumner, Whitney A., Duval, Nathan, Patterson, David, Linseman, Daniel A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4665503/ https://www.ncbi.nlm.nih.gov/pubmed/26785244 http://dx.doi.org/10.3390/antiox3040843 |
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