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Circulating HMGB1 and RAGE as Clinical Biomarkers in Malignant and Autoimmune Diseases
High molecular group box 1 (HMGB1) is a highly conserved member of the HMG-box-family; abundantly expressed in almost all human cells and released in apoptosis; necrosis or by activated immune cells. Once in the extracellular space, HMGB1 can act as a danger associated molecular pattern (DAMP), thus...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4665591/ https://www.ncbi.nlm.nih.gov/pubmed/26854151 http://dx.doi.org/10.3390/diagnostics5020219 |