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Antitumor activity of gambogic acid on NCI-H1993 xenografts via MET signaling pathway downregulation

The present study aimed to investigate the anti-tumor mechanisms of gambogic acid (GA) on NCI-H1993 xenografts in vivo. Non-small cell lung carcinoma NCI-H1993 cells, which harbor a MET gene amplification, were subcutaneously injected into athymic nude mice. The mice were randomly assigned to treatm...

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Detalles Bibliográficos
Autores principales: LI, DONGLEI, YANG, HUIWEI, LI, RUNPU, WANG, YANLI, WANG, WEIJUN, LI, DONGJIE, MA, SHAOLIN, ZHANG, XUYU
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4665713/
https://www.ncbi.nlm.nih.gov/pubmed/26722245
http://dx.doi.org/10.3892/ol.2015.3719

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