Cargando…

Valproic acid inhibits proliferation of HER2-expressing breast cancer cells by inducing cell cycle arrest and apoptosis through Hsp70 acetylation

Breast cancer encompasses a heterogeneous group of diseases at the molecular level. It is known that chemo-sensitivity of breast cancer depends on its molecular subtype. We investigated the growth inhibitory effect of valproic acid (VPA), a histone deacetylase (HDAC) inhibitor, and the mechanism of...

Descripción completa

Detalles Bibliográficos
Autores principales:	MAWATARI, TOSHIKI, NINOMIYA, ITASU, INOKUCHI, MASAFUMI, HARADA, SHINICHI, HAYASHI, HIRONORI, OYAMA, KATSUNOBU, MAKINO, ISAMU, NAKAGAWARA, HISATOSHI, MIYASHITA, TOMOHARU, TAJIMA, HIDEHIRO, TAKAMURA, HIROYUKI, FUSHIDA, SACHIO, OHTA, TETSUO
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2015
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4665753/ https://www.ncbi.nlm.nih.gov/pubmed/26497673 http://dx.doi.org/10.3892/ijo.2015.3213

Ejemplares similares

Duodenal ulcer penetration into the liver at the previous left hemihepatectomy site()
por: Hayashi, Hironori, et al.
Publicado: (2013)

Valproic acid inhibits irradiation-induced epithelial-mesenchymal transition and stem cell-like characteristics in esophageal squamous cell carcinoma
por: Kanamoto, Ayako, et al.
Publicado: (2016)

Colonic stenosis caused by infection of an intraperitoneal access port system: a rare complication of intraperitoneal chemotherapy for gastric cancer with peritoneal metastasis
por: Kinoshita, Jun, et al.
Publicado: (2014)

A Case of Severe Sepsis Presenting Marked Decrease of Neutrophils and Interesting Findings on Dynamic CT
por: Makino, Isamu, et al.
Publicado: (2015)

Extravasated platelet aggregation in liver zone 3 may correlate with the progression of sinusoidal obstruction syndrome following living donor liver transplantation: A case report
por: NAKANUMA, SHINICHI, et al.
Publicado: (2015)

Incidence of and risk factors for totally implantable vascular access device complications in patients with gastric cancer: A retrospective analysis
por: Okazaki, Mitsuyoshi, et al.
Publicado: (2019)

Effects of valproic acid on the cell cycle and apoptosis through acetylation of histone and tubulin in a scirrhous gastric cancer cell line
por: Yagi, Yasumichi, et al.
Publicado: (2010)

A phase I study of neoadjuvant chemotherapy with gemcitabine plus oral S-1 for resectable pancreatic cancer
por: TAJIMA, HIDEHIRO, et al.
Publicado: (2013)

Low-dose paclitaxel inhibits the induction of epidermal-mesenchymal transition in the human cholangiocarcinoma CCKS-1 cell line
por: HIROSE, ATSUSHI, et al.
Publicado: (2013)

A Pilot Study of Chemoradiotherapy With Weekly Docetaxel for Thoracic Esophageal Carcinoma With T4 and/or M1 Lymph Node Metastasis
por: Makino, Isamu, et al.
Publicado: (2011)

Elevated alpha1-acid glycoprotein in gastric cancer patients inhibits the anticancer effects of paclitaxel, effects restored by co-administration of erythromycin
por: Ohbatake, Yoshinao, et al.
Publicado: (2015)

Low-dose eribulin mesylate exerts antitumor effects in gastric cancer by inhibiting fibrosis via the suppression of epithelial–mesenchymal transition and acts synergistically with 5-fluorouracil
por: Kurata, Toru, et al.
Publicado: (2018)

Potential of extravasated platelet aggregation as a surrogate marker for overall survival in patients with advanced gastric cancer treated with preoperative docetaxel, cisplatin and S-1: a retrospective observational study
por: Saito, Hiroto, et al.
Publicado: (2017)

Impact of histone deacetylase 1 and metastasis-associated gene 1 expression in esophageal carcinogenesis
por: MIYASHITA, TOMOHARU, et al.
Publicado: (2014)

Multiple liver metastases of pancreatic solid pseudopapillary tumor treated with resection following chemotherapy and transcatheter arterial embolization: A case report
por: TAJIMA, HIDEHIRO, et al.
Publicado: (2015)

Importance of human peritoneal mesothelial cells in the progression, fibrosis, and control of gastric cancer: inhibition of growth and fibrosis by tranilast
por: Saito, Hiroto, et al.
Publicado: (2017)

Pioglitazone inhibits the proliferation and metastasis of human pancreatic cancer cells
por: NINOMIYA, ITASU, et al.
Publicado: (2014)

Antitumor and anti-metastatic effects of cyclooxygenase-2 inhibition by celecoxib on human colorectal carcinoma xenografts in nude mouse rectum
por: NINOMIYA, ITASU, et al.
Publicado: (2012)

Low-dose valproic acid with low-dose gemcitabine augments MHC class I-related chain A/B expression without inducing the release of soluble MHC class I-related chain A/B
por: Miyashita, Tomoharu, et al.
Publicado: (2017)

Pancreatic body adenocarcinoma with neuroendocrine tumor characteristics: A case report
por: TAJIMA, HIDEHIRO, et al.
Publicado: (2014)

A Modification of Radical Antegrade Modular Pancreatosplenectomy for Adenocarcinoma of the Left Pancreas: Significance of En Bloc Resection Including the Anterior Renal Fascia
por: Kitagawa, Hirohisa, et al.
Publicado: (2014)

Increased E-selectin in hepatic ischemia-reperfusion injury mediates liver metastasis of pancreatic cancer
por: YOSHIMOTO, KATSUHIRO, et al.
Publicado: (2012)

Bone marrow derived “fibrocytes” contribute to tumor proliferation and fibrosis in gastric cancer
por: Terai, Shiro, et al.
Publicado: (2014)

Hepatic arterial infusion chemotherapy with gemcitabine and 5-fluorouracil or oral S-1 improves the prognosis of patients with postoperative liver metastases from pancreatic cancer
por: TAJIMA, HIDEHIRO, et al.
Publicado: (2013)

Establishing a xenograft mouse model of peritoneal dissemination of gastric cancer with organ invasion and fibrosis
por: Okazaki, Mitsuyoshi, et al.
Publicado: (2017)

The effect of HIF-1α and PKM1 expression on acquisition of chemoresistance
por: Okazaki, Mitsuyoshi, et al.
Publicado: (2018)

VEGF is a target molecule for peritoneal metastasis and malignant ascites in gastric cancer: prognostic significance of VEGF in ascites and efficacy of anti-VEGF monoclonal antibody
por: Fushida, Sachio, et al.
Publicado: (2013)

Tumor-associated macrophages of the M2 phenotype contribute to progression in gastric cancer with peritoneal dissemination
por: Yamaguchi, Takahisa, et al.
Publicado: (2015)

Extravasated platelet aggregation contributes to tumor progression via the accumulation of myeloid-derived suppressor cells in gastric cancer with peritoneal metastasis
por: Yamaguchi, Takahisa, et al.
Publicado: (2020)

Evaluation of eligibility criteria in living donor liver transplantation for hepatocellular carcinoma by α-SMA-positive cancer-associated fibroblasts
por: TAKAMURA, HIROYUKI, et al.
Publicado: (2013)

Pleomorphic rhabdomyosarcoma of the liver in an adult: a rare case report
por: Okazaki, Mitsuyoshi, et al.
Publicado: (2020)

Pretreatment with a Phosphodiesterase-3 Inhibitor, Milrinone, Reduces Hepatic Ischemia-Reperfusion Injury, Minimizing Pericentral Zone-Based Liver and Small Intestinal Injury in Rats
por: Nakanuma, Shinichi, et al.
Publicado: (2020)

The role of human peritoneal mesothelial cells in the fibrosis and progression of gastric cancer
por: TSUKADA, TOMOYA, et al.
Publicado: (2012)

Low-dose paclitaxel modulates tumour fibrosis in gastric cancer
por: TSUKADA, TOMOYA, et al.
Publicado: (2013)

Dynamic switch of immunity and antitumor effects of metformin in rat spontaneous esophageal carcinogenesis
por: Takei, Ryohei, et al.
Publicado: (2021)

Correction to: Dynamic switch of immunity and antitumor effects of metformin in rat spontaneous esophageal carcinogenesis
por: Takei, Ryohei, et al.
Publicado: (2021)

Adiponectin receptor-1 expression is associated with good prognosis in gastric cancer
por: Tsukada, Tomoya, et al.
Publicado: (2011)

Multidisciplinary therapy for scirrhous gastric cancer: a retrospective analysis and proposal of new treatment strategy
por: Fushida, Sachio, et al.
Publicado: (2018)

Treatment of capecitabine-induced hand-foot syndrome using a topical retinoid: A case report
por: INOKUCHI, MASAFUMI, et al.
Publicado: (2014)

Isolated adrenocorticotropic hormone deficiency development during chemotherapy for gastric cancer: a case report
por: Kinoshita, Jun, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_a91aokilbr4d414hgasbpeha9n