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EML4-ALK translocation is associated with early onset of disease and other clinicopathological features in Chinese female never-smokers with non-small-cell lung cancer

Non-small-cell lung cancer (NSCLC) with echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase (EML4-ALK) translocation is resistant to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs), including gefitinib and erlotinib, but responds to the ALK-TKI crizo...

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Detalles Bibliográficos
Autores principales: REN, WEIHONG, ZHANG, BO, MA, JIE, LI, WENCAI, LAN, JIANYUN, MEN, HUI, ZHANG, QINXIAN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4665761/
https://www.ncbi.nlm.nih.gov/pubmed/26788139
http://dx.doi.org/10.3892/ol.2015.3740