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Haplotypes of the endothelial protein C receptor (EPCR) gene are not associated with severe malaria in Tanzania

BACKGROUND: Endothelial protein C receptor (EPCR) was recently identified as a key receptor for Plasmodium falciparum erythrocyte membrane protein 1 mediating sequestration of P. falciparum-infected erythrocytes in patients suffering from severe malaria. Soluble EPCR (sEPCR) inhibits binding of P. f...

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Detalles Bibliográficos
Autores principales: Hansson, Helle Holm, Turner, Louise, Møller, Line, Wang, Christian William, Minja, Daniel T. R., Gesase, Samwel, Mmbando, Bruno, Bygbjerg, Ib Christian, Theander, Thor G., Lusingu, John P. A., Alifrangis, Michael, Lavstsen, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666078/
https://www.ncbi.nlm.nih.gov/pubmed/26620701
http://dx.doi.org/10.1186/s12936-015-1007-6