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Focal adhesions are foci for tyrosine-based signal transduction via GIV/Girdin and G proteins
GIV/Girdin is a multimodular signal transducer and a bona fide metastasis-related protein. As a guanidine exchange factor (GEF), GIV modulates signals initiated by growth factors (chemical signals) by activating the G protein Gαi. Here we report that mechanical signals triggered by the extracellular...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666128/ https://www.ncbi.nlm.nih.gov/pubmed/26446841 http://dx.doi.org/10.1091/mbc.E15-07-0496 |