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Efficient APC/C substrate degradation in cells undergoing mitotic exit depends on K11 ubiquitin linkages

The ubiquitin proteasome system (UPS) directs programmed destruction of key cellular regulators via posttranslational modification of its targets with polyubiquitin chains. These commonly contain Lys-48 (K48)–directed ubiquitin linkages, but chains containing atypical Lys-11 (K11) linkages also targ...

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Detalles Bibliográficos
Autores principales:	Min, Mingwei, Mevissen, Tycho E. T., De Luca, Maria, Komander, David, Lindon, Catherine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2015
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666129/ https://www.ncbi.nlm.nih.gov/pubmed/26446837 http://dx.doi.org/10.1091/mbc.E15-02-0102

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