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gp78 functions downstream of Hrd1 to promote degradation of misfolded proteins of the endoplasmic reticulum

Eukaryotic cells eliminate misfolded proteins from the endoplasmic reticulum (ER) via a conserved process termed ER-associated degradation (ERAD). Central regulators of the ERAD system are membrane-bound ubiquitin ligases, which are thought to channel misfolded proteins through the ER membrane durin...

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Detalles Bibliográficos
Autores principales:	Zhang, Ting, Xu, Yue, Liu, Yanfen, Ye, Yihong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2015
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666138/ https://www.ncbi.nlm.nih.gov/pubmed/26424800 http://dx.doi.org/10.1091/mbc.E15-06-0354

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