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Herpes simplex virus 1 UL41 protein abrogates the antiviral activity of hZAP by degrading its mRNA

BACKGROUND: The zinc finger antiviral protein (ZAP) is a host restriction factor that inhibits the replication of various viruses by degradation of certain viral mRNA. However, previous study demonstrated that ectopic expression of rat ZAP did not suppress the replication of herpes simplex virus typ...

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Detalles Bibliográficos
Autores principales: Su, Chenhe, Zhang, Jie, Zheng, Chunfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666169/
https://www.ncbi.nlm.nih.gov/pubmed/26625984
http://dx.doi.org/10.1186/s12985-015-0433-y