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Backtracking behavior in viral RNA-dependent RNA polymerase provides the basis for a second initiation site

Transcription in RNA viruses is highly dynamic, with a variety of pauses interrupting nucleotide addition by RNA-dependent RNA polymerase (RdRp). For example, rare but lengthy pauses (>20 s) have been linked to backtracking for viral single-subunit RdRps. However, while such backtracking has been...

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Detalles Bibliográficos
Autores principales:	Dulin, David, Vilfan, Igor D., Berghuis, Bojk A., Poranen, Minna M., Depken, Martin, Dekker, Nynke H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2015
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666362/ https://www.ncbi.nlm.nih.gov/pubmed/26496948 http://dx.doi.org/10.1093/nar/gkv1098

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