DNA targeting by the type I-G and type I-A CRISPR–Cas systems of Pyrococcus furiosus

CRISPR–Cas systems silence plasmids and viruses in prokaryotes. CRISPR–Cas effector complexes contain CRISPR RNAs (crRNAs) that include sequences captured from invaders and direct CRISPR-associated (Cas) proteins to destroy corresponding invader nucleic acids. Pyrococcus furiosus (Pfu) harbors three...

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Detalles Bibliográficos
Autores principales: Elmore, Joshua, Deighan, Trace, Westpheling, Jan, Terns, Rebecca M., Terns, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666368/
https://www.ncbi.nlm.nih.gov/pubmed/26519471
http://dx.doi.org/10.1093/nar/gkv1140

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