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Thermodynamic fingerprints of ligand binding to human telomeric G-quadruplexes

Thermodynamic studies of ligand binding to human telomere (ht) DNA quadruplexes, as a rule, neglect the involvement of various ht-DNA conformations in the binding process. Therefore, the thermodynamic driving forces and the mechanisms of ht-DNA G-quadruplex-ligand recognition remain poorly understoo...

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Detalles Bibliográficos
Autores principales: Bončina, Matjaž, Podlipnik, Črtomir, Piantanida, Ivo, Eilmes, Julita, Teulade-Fichou, Marie-Paule, Vesnaver, Gorazd, Lah, Jurij
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666371/
https://www.ncbi.nlm.nih.gov/pubmed/26546516
http://dx.doi.org/10.1093/nar/gkv1167

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