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Xanthine and 8-oxoguanine in G-quadruplexes: formation of a G·G·X·O tetrad

G-quadruplexes are four-stranded structures built from stacked G-tetrads (G·G·G·G), which are planar cyclical assemblies of four guanine bases interacting through Hoogsteen hydrogen bonds. A G-quadruplex containing a single guanine analog substitution, such as 8-oxoguanine (O) or xanthine (X), would...

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Detalles Bibliográficos
Autores principales:	Cheong, Vee Vee, Heddi, Brahim, Lech, Christopher Jacques, Phan, Anh Tuân
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2015
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666386/ https://www.ncbi.nlm.nih.gov/pubmed/26400177 http://dx.doi.org/10.1093/nar/gkv826

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