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Specific Interaction between eEF1A and HIV RT Is Critical for HIV-1 Reverse Transcription and a Potential Anti-HIV Target

Reverse transcription is the central defining feature of HIV-1 replication. We previously reported that the cellular eukaryotic elongation factor 1 (eEF1) complex associates with the HIV-1 reverse transcription complex (RTC) and the association is important for late steps of reverse transcription. H...

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Detalles Bibliográficos
Autores principales: Li, Dongsheng, Wei, Ting, Rawle, Daniel J., Qin, Fangyun, Wang, Rui, Soares, Dinesh C., Jin, Hongping, Sivakumaran, Haran, Lin, Min-Hsuan, Spann, Kirsten, Abbott, Catherine M., Harrich, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666417/
https://www.ncbi.nlm.nih.gov/pubmed/26624286
http://dx.doi.org/10.1371/journal.ppat.1005289