Follicular Dendritic Cells Retain Infectious HIV in Cycling Endosomes

Despite the success of antiretroviral therapy (ART), it does not cure Human Immunodeficiency Virus (HIV) and discontinuation results in viral rebound. Follicular dendritic cells (FDC) are in direct contact with CD4+ T cells and they retain intact antigen for prolonged periods. We found that human FD...

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Detalles Bibliográficos
Autores principales: Heesters, Balthasar A., Lindqvist, Madelene, Vagefi, Parsia A., Scully, Eileen P., Schildberg, Frank A., Altfeld, Marcus, Walker, Bruce D., Kaufmann, Daniel E., Carroll, Michael C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666623/
https://www.ncbi.nlm.nih.gov/pubmed/26623655
http://dx.doi.org/10.1371/journal.ppat.1005285

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