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The SUMOylation Pathway Restricts Gene Transduction by Adeno-Associated Viruses

Adeno-associated viruses are members of the genus dependoviruses of the parvoviridae family. AAV vectors are considered promising vectors for gene therapy and genetic vaccination as they can be easily produced, are highly stable and non-pathogenic. Nevertheless, transduction of cells in vitro and in...

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Detalles Bibliográficos
Autores principales: Hölscher, Christina, Sonntag, Florian, Henrich, Katharina, Chen, Qingxin, Beneke, Jürgen, Matula, Petr, Rohr, Karl, Kaderali, Lars, Beil, Nina, Erfle, Holger, Kleinschmidt, Jürgen A., Müller, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666624/
https://www.ncbi.nlm.nih.gov/pubmed/26625259
http://dx.doi.org/10.1371/journal.ppat.1005281

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