Large Neutral Amino Acid Supplementation Exerts Its Effect through Three Synergistic Mechanisms: Proof of Principle in Phenylketonuria Mice

BACKGROUND: Phenylketonuria (PKU) was the first disorder in which severe neurocognitive dysfunction could be prevented by dietary treatment. However, despite this effect, neuropsychological outcome in PKU still remains suboptimal and the phenylalanine-restricted diet is very demanding. To improve ne...

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Detalles Bibliográficos
Autores principales: van Vliet, Danique, Bruinenberg, Vibeke M., Mazzola, Priscila N., van Faassen, Martijn H. J. R., de Blaauw, Pim, Kema, Ido P., Heiner-Fokkema, M. Rebecca, van Anholt, Rogier D., van der Zee, Eddy A., van Spronsen, Francjan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666635/
https://www.ncbi.nlm.nih.gov/pubmed/26624009
http://dx.doi.org/10.1371/journal.pone.0143833

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