Contrasting genetic architectures of schizophrenia and other complex diseases using fast variance components analysis

Heritability analyses of GWAS cohorts have yielded important insights into complex disease architecture, and increasing sample sizes hold the promise of further discoveries. Here, we analyze the genetic architecture of schizophrenia in 49,806 samples from the PGC, and nine complex diseases in 54,734...

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Detalles Bibliográficos
Autores principales: Loh, Po-Ru, Bhatia, Gaurav, Gusev, Alexander, Finucane, Hilary K, Bulik-Sullivan, Brendan K, Pollack, Samuela J, de Candia, Teresa R, Lee, Sang Hong, Wray, Naomi R, Kendler, Kenneth S, O’Donovan, Michael C, Neale, Benjamin M, Patterson, Nick, Price, Alkes L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666835/
https://www.ncbi.nlm.nih.gov/pubmed/26523775
http://dx.doi.org/10.1038/ng.3431

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666835/
https://www.ncbi.nlm.nih.gov/pubmed/26523775
http://dx.doi.org/10.1038/ng.3431

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