Left Ventricular Thrombus as a Complication of Clozapine-Induced Cardiomyopathy: A Case Report and Brief Literature Review

A 48-year-old male with history of schizoaffective disorder on clozapine presented with chest pain, dyspnea, and new left bundle branch block. He underwent coronary angiography, which revealed no atherosclerosis. The patient's workup was unrevealing for a cause for the cardiomyopathy and thus i...

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Detalles Bibliográficos
Autores principales: Malik, Shahbaz A., Malik, Sarah, Dowsley, Taylor F., Singh, Balwinder
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667025/
https://www.ncbi.nlm.nih.gov/pubmed/26664756
http://dx.doi.org/10.1155/2015/835952
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author Malik, Shahbaz A.
Malik, Sarah
Dowsley, Taylor F.
Singh, Balwinder
author_facet Malik, Shahbaz A.
Malik, Sarah
Dowsley, Taylor F.
Singh, Balwinder
author_sort Malik, Shahbaz A.
collection PubMed
description A 48-year-old male with history of schizoaffective disorder on clozapine presented with chest pain, dyspnea, and new left bundle branch block. He underwent coronary angiography, which revealed no atherosclerosis. The patient's workup was unrevealing for a cause for the cardiomyopathy and thus it was thought that clozapine was the offending agent. The patient was taken off clozapine and started on guideline directed heart failure therapy. During the course of hospitalization, he was also discovered to have a left ventricular (LV) thrombus for which he received anticoagulation. To our knowledge, this is the first case report of clozapine-induced cardiomyopathy complicated by a LV thrombus.
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spelling pubmed-46670252015-12-09 Left Ventricular Thrombus as a Complication of Clozapine-Induced Cardiomyopathy: A Case Report and Brief Literature Review Malik, Shahbaz A. Malik, Sarah Dowsley, Taylor F. Singh, Balwinder Case Rep Cardiol Case Report A 48-year-old male with history of schizoaffective disorder on clozapine presented with chest pain, dyspnea, and new left bundle branch block. He underwent coronary angiography, which revealed no atherosclerosis. The patient's workup was unrevealing for a cause for the cardiomyopathy and thus it was thought that clozapine was the offending agent. The patient was taken off clozapine and started on guideline directed heart failure therapy. During the course of hospitalization, he was also discovered to have a left ventricular (LV) thrombus for which he received anticoagulation. To our knowledge, this is the first case report of clozapine-induced cardiomyopathy complicated by a LV thrombus. Hindawi Publishing Corporation 2015 2015-11-18 /pmc/articles/PMC4667025/ /pubmed/26664756 http://dx.doi.org/10.1155/2015/835952 Text en Copyright © 2015 Shahbaz A. Malik et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Malik, Shahbaz A.
Malik, Sarah
Dowsley, Taylor F.
Singh, Balwinder
Left Ventricular Thrombus as a Complication of Clozapine-Induced Cardiomyopathy: A Case Report and Brief Literature Review
title Left Ventricular Thrombus as a Complication of Clozapine-Induced Cardiomyopathy: A Case Report and Brief Literature Review
title_full Left Ventricular Thrombus as a Complication of Clozapine-Induced Cardiomyopathy: A Case Report and Brief Literature Review
title_fullStr Left Ventricular Thrombus as a Complication of Clozapine-Induced Cardiomyopathy: A Case Report and Brief Literature Review
title_full_unstemmed Left Ventricular Thrombus as a Complication of Clozapine-Induced Cardiomyopathy: A Case Report and Brief Literature Review
title_short Left Ventricular Thrombus as a Complication of Clozapine-Induced Cardiomyopathy: A Case Report and Brief Literature Review
title_sort left ventricular thrombus as a complication of clozapine-induced cardiomyopathy: a case report and brief literature review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667025/
https://www.ncbi.nlm.nih.gov/pubmed/26664756
http://dx.doi.org/10.1155/2015/835952
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