Cargando…

Altered Innate Immune Responses in Neutrophils from Patients with Well- and Suboptimally Controlled Asthma

Background. Respiratory infections are a major cause of asthma exacerbations where neutrophilic inflammation dominates and is associated with steroid refractory asthma. Structural airway cells in asthma differ from nonasthmatics; however it is unknown if neutrophils differ. We investigated neutrophi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tang, Francesca S. M., Foxley, Gloria J., Gibson, Peter G., Burgess, Janette K., Baines, Katherine J., Oliver, Brian G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667029/ https://www.ncbi.nlm.nih.gov/pubmed/26663987 http://dx.doi.org/10.1155/2015/219374

Ejemplares similares

Differential neutrophil activation in viral infections: Enhanced TLR‐7/8‐mediated CXCL8 release in asthma
por: Tang, Francesca S.M., et al.
Publicado: (2015)

A novel immunomodulatory function of neutrophils on rhinovirus-activated monocytes in vitro
por: Tang, Francesca S M, et al.
Publicado: (2016)

How to step down asthma preventer treatment in patients with well-controlled asthma – more is not always better
por: Reddel, Helen K, et al.
Publicado: (2022)

An altered sputum macrophage transcriptome contributes to the neutrophilic asthma endotype
por: Fricker, Michael, et al.
Publicado: (2021)

Sputum colour can identify patients with neutrophilic inflammation in asthma
por: Pabreja, Kavita, et al.
Publicado: (2017)

Airway monocyte modulation relates to tumour necrosis factor dysregulation in neutrophilic asthma
por: Niessen, Natalie M., et al.
Publicado: (2021)

Asthma Is Associated with Multiple Alterations in Anti-Viral Innate Signalling Pathways
por: Pritchard, Antonia L., et al.
Publicado: (2014)

Suboptimal asthma care for immigrant children: results of an audit study
por: Urbanus-van Laar, JJ Nathalie, et al.
Publicado: (2008)

How Can Microarrays Unlock Asthma?
por: Faiz, Alen, et al.
Publicado: (2012)

Anti-inflammatory deficiencies in neutrophilic asthma: reduced galectin-3 and IL-1RA/IL-1β
por: Gao, Peng, et al.
Publicado: (2015)

Children With Asthma Have Impaired Innate Immunity and Increased Numbers of Type 2 Innate Lymphoid Cells Compared With Healthy Controls
por: Hosseini, Banafshe, et al.
Publicado: (2021)

Is low dose inhaled corticosteroid therapy as effective for inflammation and remodeling in asthma? A randomized, parallel group study
por: Baraket, Melissa, et al.
Publicado: (2012)

The Effects of Increasing Fruit and Vegetable Intake in Children with Asthma on the Modulation of Innate Immune Responses
por: Hosseini, Banafsheh, et al.
Publicado: (2022)

Innate Lymphoid Cells Are Required to Induce Airway Hyperreactivity in a Murine Neutrophilic Asthma Model
por: Jonckheere, Anne-Charlotte, et al.
Publicado: (2022)

Neutrophils: Innate Effectors of TB Resistance?
por: Kroon, Elouise E., et al.
Publicado: (2018)

Innate Immune Responses Are Increased in Chronic Obstructive Pulmonary Disease
por: Baines, Katherine Joanne, et al.
Publicado: (2011)

Factors Associated with Suboptimal Control of Asthma among Adult Asthma Patients: A Cross-sectional Study
por: Lual, Kuol Peter, et al.
Publicado: (2021)

Blood Neutrophils In COPD But Not Asthma Exhibit A Primed Phenotype With Downregulated CD62L Expression
por: Lokwani, Ravi, et al.
Publicado: (2019)

The Residual Innate Lymphoid Cells in NFIL3-Deficient Mice Support Suboptimal Maternal Adaptations to Pregnancy
por: Boulenouar, Selma, et al.
Publicado: (2016)

Corrigendum: Innate lymphoid cells are required to induce airway hyperreactivity in a murine neutrophilic asthma model
por: Jonckheere, Anne-Charlotte, et al.
Publicado: (2022)

Neutrophils and Asthma
por: Yamasaki, Akira, et al.
Publicado: (2022)

Suboptimal evolutionary novel environments promote singular altered gravity responses of transcriptome during Drosophila metamorphosis
por: Herranz, Raul, et al.
Publicado: (2013)

Determinants and impact of suboptimal asthma control in Europe: The INTERNATIONAL CROSS-SECTIONAL AND LONGITUDINAL ASSESSMENT ON ASTHMA CONTROL (LIAISON) study
por: Braido, Fulvio, et al.
Publicado: (2016)

Azithromycin treatment modifies airway and blood gene expression networks in neutrophilic COPD
por: Baines, Katherine J., et al.
Publicado: (2018)

Validation of the Flourishing Scale in a sample of people with suboptimal levels of mental well-being
por: Schotanus-Dijkstra, Marijke, et al.
Publicado: (2016)

Visceral Leishmaniasis Patients Display Altered Composition and Maturity of Neutrophils as well as Impaired Neutrophil Effector Functions
por: Yizengaw, Endalew, et al.
Publicado: (2016)

Suboptimal analysis using 'optimal' cutpoints.
por: Altman, D. G.
Publicado: (1998)

Suboptimally controlled asthma in patients treated with inhaled ICS/LABA: prevalence, risk factors, and outcomes
por: Zhang, Shiyuan, et al.
Publicado: (2023)

Theory of suboptimal decisions: decomposition and aggregation
por: Pervozvanskii, A A, et al.
Publicado: (1988)

A serological biomarker of type I collagen degradation is related to a more severe, high neutrophilic, obese asthma subtype
por: Rønnow, Sarah Rank, et al.
Publicado: (2022)

Neutrophils: Their Role in Innate and Adaptive Immunity
por: Rosales, Carlos, et al.
Publicado: (2016)

Soluble Fibre Meal Challenge Reduces Airway Inflammation and Expression of GPR43 and GPR41 in Asthma
por: Halnes, Isabel, et al.
Publicado: (2017)

Fibulin-1 Is Increased in Asthma – A Novel Mediator of Airway Remodeling?
por: Lau, Justine Y., et al.
Publicado: (2010)

Suboptimal compliance to aerosol therapy in pediatric asthma: A prospective cohort study from Eastern India
por: Sinha, Rajasree, et al.
Publicado: (2019)

Suboptimal Control of Asthma Among Diverse Patients: A US Mixed Methods Focus Group Study
por: George, Maureen, et al.
Publicado: (2022)

The Effect of Azithromycin in Adults with Stable Neutrophilic COPD: A Double Blind Randomised, Placebo Controlled Trial
por: Simpson, Jodie L., et al.
Publicado: (2014)

A Quantitative Proteomic Approach to Identify Significantly Altered Protein Networks in the Serum of Patients with Lymphangioleiomyomatosis (LAM)
por: Banville, Nessa, et al.
Publicado: (2014)

Innate lymphocyte cells in asthma phenotypes
por: Ozyigit, Leyla Pur, et al.
Publicado: (2015)

Combining eye and hand in search is suboptimal
por: Liesker, Hanneke, et al.
Publicado: (2009)

Airway β-Defensin-1 Protein Is Elevated in COPD and Severe Asthma
por: Baines, Katherine J., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_um5c6o00pmsjsrc10as1qtbf2i