Transfection of microRNA Mimics Should Be Used with Caution

Transient transfection of chemically synthesized microRNA (miRNA) mimics is being used extensively to study the functions and mechanisms of endogenous miRNAs. However, it remains unclear whether transfected miRNAs behave similarly to endogenous miRNAs. Here we show that transient transfection of miR...

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Detalles Bibliográficos
Autores principales: Jin, Hyun Yong, Gonzalez-Martin, Alicia, Miletic, Ana V., Lai, Maoyi, Knight, Sarah, Sabouri-Ghomi, Mohsen, Head, Steven R., Macauley, Matthew S., Rickert, Robert C., Xiao, Changchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667072/
https://www.ncbi.nlm.nih.gov/pubmed/26697058
http://dx.doi.org/10.3389/fgene.2015.00340

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