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Early-Stage White Matter Lesions Detected by Multispectral MRI Segmentation Predict Progressive Cognitive Decline
White matter lesions (WML) are the main brain imaging surrogate of cerebral small-vessel disease. A new MRI tissue segmentation method, based on a discriminative clustering approach without explicit model-based added prior, detects partial WML volumes, likely representing very early-stage changes in...
Autores principales: | Jokinen, Hanna, Gonçalves, Nicolau, Vigário, Ricardo, Lipsanen, Jari, Fazekas, Franz, Schmidt, Reinhold, Barkhof, Frederik, Madureira, Sofia, Verdelho, Ana, Inzitari, Domenico, Pantoni, Leonardo, Erkinjuntti, Timo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667087/ https://www.ncbi.nlm.nih.gov/pubmed/26696814 http://dx.doi.org/10.3389/fnins.2015.00455 |
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