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Tumor-selective peptide-carrier delivery of Paclitaxel increases in vivo activity of the drug

Taxanes are highly effective chemotherapeutic drugs against proliferating cancer and an established option in the standard treatment of ovarian and breast cancer. However, treatment with paclitaxel is associated with severe side effects, including sensory axonal neuropathy, and its poor solubility i...

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Detalles Bibliográficos
Autores principales: Brunetti, Jlenia, Pillozzi, Serena, Falciani, Chiara, Depau, Lorenzo, Tenori, Eleonora, Scali, Silvia, Lozzi, Luisa, Pini, Alessandro, Arcangeli, Annarosa, Menichetti, Stefano, Bracci, Luisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667195/
https://www.ncbi.nlm.nih.gov/pubmed/26626158
http://dx.doi.org/10.1038/srep17736