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Tumor-selective peptide-carrier delivery of Paclitaxel increases in vivo activity of the drug
Taxanes are highly effective chemotherapeutic drugs against proliferating cancer and an established option in the standard treatment of ovarian and breast cancer. However, treatment with paclitaxel is associated with severe side effects, including sensory axonal neuropathy, and its poor solubility i...
Autores principales: | Brunetti, Jlenia, Pillozzi, Serena, Falciani, Chiara, Depau, Lorenzo, Tenori, Eleonora, Scali, Silvia, Lozzi, Luisa, Pini, Alessandro, Arcangeli, Annarosa, Menichetti, Stefano, Bracci, Luisa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667195/ https://www.ncbi.nlm.nih.gov/pubmed/26626158 http://dx.doi.org/10.1038/srep17736 |
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