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Human embryonic stem cell-derived mesenchymal cells preserve kidney function and extend lifespan in NZB/W F1 mouse model of lupus nephritis
Adult tissue-derived mesenchymal stromal cells (MSCs) are showing promise in clinical trials for systemic lupus erythematosus (SLE). However, the inability to manufacture large quantities of functional cells from a single donor as well as donor-dependent variability in quality limits their clinical...
Autores principales: | Thiel, Austin, Yavanian, Gregory, Nastke, Maria-Dorothea, Morales, Peter, Kouris, Nicholas A., Kimbrel, Erin A., Lanza, Robert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667213/ https://www.ncbi.nlm.nih.gov/pubmed/26628350 http://dx.doi.org/10.1038/srep17685 |
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