Oppositional COMT Val158Met effects on resting state functional connectivity in adolescents and adults

Prefrontal dopamine levels are relatively increased in adolescence compared to adulthood. Genetic variation of COMT (COMT Val158Met) results in lower enzymatic activity and higher dopamine availability in Met carriers. Given the dramatic changes of synaptic dopamine during adolescence, it has been s...

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Detalles Bibliográficos
Autores principales: Meyer, Bernhard M., Huemer, Julia, Rabl, Ulrich, Boubela, Roland N., Kalcher, Klaudius, Berger, Andreas, Banaschewski, Tobias, Barker, Gareth, Bokde, Arun, Büchel, Christian, Conrod, Patricia, Desrivières, Sylvane, Flor, Herta, Frouin, Vincent, Gallinat, Jurgen, Garavan, Hugh, Heinz, Andreas, Ittermann, Bernd, Jia, Tianye, Lathrop, Mark, Martinot, Jean-Luc, Nees, Frauke, Rietschel, Marcella, Smolka, Michael N., Bartova, Lucie, Popovic, Ana, Scharinger, Christian, Sitte, Harald H., Steiner, Hans, Friedrich, Max H., Kasper, Siegfried, Perkmann, Thomas, Praschak-Rieder, Nicole, Haslacher, Helmuth, Esterbauer, Harald, Moser, Ewald, Schumann, Gunter, Pezawas, Lukas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667398/
https://www.ncbi.nlm.nih.gov/pubmed/25319752
http://dx.doi.org/10.1007/s00429-014-0895-5

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