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Engineering and expression of a human rotavirus candidate vaccine in Nicotiana benthamiana

BACKGROUND: Human rotaviruses are the main cause of severe gastroenteritis in children and are responsible for over 500 000 deaths annually. There are two live rotavirus vaccines currently available, one based on human rotavirus serotype G1P[8], and the other a G1-G4 P[8] pentavalent vaccine. Howeve...

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Detalles Bibliográficos
Autores principales:	Pêra, Francisco F. P. G., Mutepfa, David L. R., Khan, Ayesha M., Els, Johann H., Mbewana, Sandiswa, van Dijk, Alberdina A. A., Rybicki, Edward P., Hitzeroth, Inga I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667453/ https://www.ncbi.nlm.nih.gov/pubmed/26626122 http://dx.doi.org/10.1186/s12985-015-0436-8

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