MicroRNA-186 induces sensitivity of ovarian cancer cells to paclitaxel and cisplatin by targeting ABCB1

BACKGROUND: Recent studies have shown that microRNAs may regulate the ABCB1 gene (ATP-binding cassette, sub-family B [MDR/TAP], member 1). Computational programs have predicted that the 3’-untranslated region (3’-UTR) of ABCB1 contains a potential miRNA-binding site for miR-186. Here, we investigate...

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Detalles Bibliográficos
Autores principales: Sun, Kai-Xuan, Jiao, Jin-Wen, Chen, Shuo, Liu, Bo-Liang, Zhao, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667519/
https://www.ncbi.nlm.nih.gov/pubmed/26626440
http://dx.doi.org/10.1186/s13048-015-0207-6

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