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Imaging Brain Development: Benefiting from Individual Variability
Human brain development is a complex process that evolves from early childhood to young adulthood. Major advances in brain imaging are increasingly being used to characterize the developing brain. These advances have further helped to elucidate the dynamic maturational processes that lead to the eme...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Libertas Academica
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667561/ https://www.ncbi.nlm.nih.gov/pubmed/26648753 http://dx.doi.org/10.4137/JEN.S32734 |
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author | Sharda, Megha Foster, Nicholas E.V. Hyde, Krista L. |
author_facet | Sharda, Megha Foster, Nicholas E.V. Hyde, Krista L. |
author_sort | Sharda, Megha |
collection | PubMed |
description | Human brain development is a complex process that evolves from early childhood to young adulthood. Major advances in brain imaging are increasingly being used to characterize the developing brain. These advances have further helped to elucidate the dynamic maturational processes that lead to the emergence of complex cognitive abilities in both typical and atypical development. However, conventional approaches involve categorical group comparison models and tend to disregard the role of widespread interindividual variability in brain development. This review highlights how this variability can inform our understanding of developmental processes. The latest studies in the field of brain development are reviewed, with a particular focus on the role of individual variability and the consequent heterogeneity in brain structural and functional development. This review also highlights how such heterogeneity might be utilized to inform our understanding of complex neuropsychiatric disorders and recommends the use of more dimensional approaches to study brain development. |
format | Online Article Text |
id | pubmed-4667561 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Libertas Academica |
record_format | MEDLINE/PubMed |
spelling | pubmed-46675612015-12-08 Imaging Brain Development: Benefiting from Individual Variability Sharda, Megha Foster, Nicholas E.V. Hyde, Krista L. J Exp Neurosci Review Human brain development is a complex process that evolves from early childhood to young adulthood. Major advances in brain imaging are increasingly being used to characterize the developing brain. These advances have further helped to elucidate the dynamic maturational processes that lead to the emergence of complex cognitive abilities in both typical and atypical development. However, conventional approaches involve categorical group comparison models and tend to disregard the role of widespread interindividual variability in brain development. This review highlights how this variability can inform our understanding of developmental processes. The latest studies in the field of brain development are reviewed, with a particular focus on the role of individual variability and the consequent heterogeneity in brain structural and functional development. This review also highlights how such heterogeneity might be utilized to inform our understanding of complex neuropsychiatric disorders and recommends the use of more dimensional approaches to study brain development. Libertas Academica 2015-12-01 /pmc/articles/PMC4667561/ /pubmed/26648753 http://dx.doi.org/10.4137/JEN.S32734 Text en © 2015 the author(s), publisher and licensee Libertas Academica Ltd. This is an open access article published under the Creative Commons CC-BY-NC 3.0 license. |
spellingShingle | Review Sharda, Megha Foster, Nicholas E.V. Hyde, Krista L. Imaging Brain Development: Benefiting from Individual Variability |
title | Imaging Brain Development: Benefiting from Individual Variability |
title_full | Imaging Brain Development: Benefiting from Individual Variability |
title_fullStr | Imaging Brain Development: Benefiting from Individual Variability |
title_full_unstemmed | Imaging Brain Development: Benefiting from Individual Variability |
title_short | Imaging Brain Development: Benefiting from Individual Variability |
title_sort | imaging brain development: benefiting from individual variability |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667561/ https://www.ncbi.nlm.nih.gov/pubmed/26648753 http://dx.doi.org/10.4137/JEN.S32734 |
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