Intronic regulation of Aire expression by Jmjd6 for self-tolerance induction in the thymus

The thymus has spatially distinct microenvironments, the cortex and the medulla, where the developing T-cells are selected to mature or die through the interaction with thymic stromal cells. To establish the immunological self in the thymus, medullary thymic epithelial cells (mTECs) express diverse...

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Detalles Bibliográficos
Autores principales: Yanagihara, Toyoshi, Sanematsu, Fumiyuki, Sato, Tetsuya, Uruno, Takehito, Duan, Xuefeng, Tomino, Takahiro, Harada, Yosuke, Watanabe, Mayuki, Wang, Yuqing, Tanaka, Yoshihiko, Nakanishi, Yoichi, Suyama, Mikita, Yoshinori, Fukui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667615/
https://www.ncbi.nlm.nih.gov/pubmed/26531897
http://dx.doi.org/10.1038/ncomms9820

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