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Targeting of SUMO substrates to a Cdc48–Ufd1–Npl4 segregase and STUbL pathway in fission yeast
In eukaryotes, the conjugation of proteins to the small ubiquitin-like modifier (SUMO) regulates numerous cellular functions. A proportion of SUMO conjugates are targeted for degradation by SUMO-targeted ubiquitin ligases (STUbLs) and it has been proposed that the ubiquitin-selective chaperone Cdc48...
Autores principales: | Køhler, Julie Bonne, Tammsalu, Triin, Jørgensen, Maria Mønster, Steen, Nana, Hay, Ronald Thomas, Thon, Geneviève |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667616/ https://www.ncbi.nlm.nih.gov/pubmed/26537787 http://dx.doi.org/10.1038/ncomms9827 |
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