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Localized reconstruction of subunits from electron cryomicroscopy images of macromolecular complexes

Electron cryomicroscopy can yield near-atomic resolution structures of highly ordered macromolecular complexes. Often however some subunits bind in a flexible manner, have different symmetry from the rest of the complex, or are present in sub-stoichiometric amounts, limiting the attainable resolutio...

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Detalles Bibliográficos
Autores principales: Ilca, Serban L., Kotecha, Abhay, Sun, Xiaoyu, Poranen, Minna M., Stuart, David I., Huiskonen, Juha T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667630/
https://www.ncbi.nlm.nih.gov/pubmed/26534841
http://dx.doi.org/10.1038/ncomms9843