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ADAR1 Facilitates HIV-1 Replication in Primary CD4(+) T Cells

Unlike resting CD4(+) T cells, activated CD4(+)T cells are highly susceptible to infection of human immunodeficiency virus 1 (HIV-1). HIV-1 infects T cells and macrophages without activating the nucleic acid sensors and the anti-viral type I interferon response. Adenosine deaminase acting on RNA 1 (...

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Detalles Bibliográficos
Autores principales:	Cuadrado, Eloy, Booiman, Thijs, van Hamme, John L., Jansen, Machiel H., van Dort, Karel A., Vanderver, Adeline, Rice, Gillian I., Crow, Yanick J., Kootstra, Neeltje A., Kuijpers, Taco W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667845/ https://www.ncbi.nlm.nih.gov/pubmed/26629815 http://dx.doi.org/10.1371/journal.pone.0143613

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