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Functional Mimetics of the HIV-1 CCR5 Co-Receptor Displayed on the Surface of Magnetic Liposomes

Chemokine G protein coupled receptors, principally CCR5 or CXCR4, function as co-receptors for HIV-1 entry into CD4(+) T cells. Initial binding of the viral envelope glycoprotein (Env) gp120 subunit to the host CD4 receptor induces a cascade of structural conformational changes that lead to the form...

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Detalles Bibliográficos
Autores principales: Kuzmina, Alona, Vaknin, Karin, Gdalevsky, Garik, Vyazmensky, Maria, Marks, Robert S., Taube, Ran, Engel, Stanislav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667905/
https://www.ncbi.nlm.nih.gov/pubmed/26629902
http://dx.doi.org/10.1371/journal.pone.0144043