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Glucose Evokes Rapid Ca(2+) and Cyclic AMP Signals by Activating the Cell-Surface Glucose-Sensing Receptor in Pancreatic β-Cells
Glucose is a primary stimulator of insulin secretion in pancreatic β-cells. High concentration of glucose has been thought to exert its action solely through its metabolism. In this regard, we have recently reported that glucose also activates a cell-surface glucose-sensing receptor and facilitates...
Autores principales: | Nakagawa, Yuko, Nagasawa, Masahiro, Medina, Johan, Kojima, Itaru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667910/ https://www.ncbi.nlm.nih.gov/pubmed/26630567 http://dx.doi.org/10.1371/journal.pone.0144053 |
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