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Top2 and Sgs1-Top3 Act Redundantly to Ensure rDNA Replication Termination
Faithful DNA replication with correct termination is essential for genome stability and transmission of genetic information. Here we have investigated the potential roles of Topoisomerase II (Top2) and the RecQ helicase Sgs1 during late stages of replication. We find that cells lacking Top2 and Sgs1...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4668019/ https://www.ncbi.nlm.nih.gov/pubmed/26630413 http://dx.doi.org/10.1371/journal.pgen.1005697 |