Cargando…

Streptozocin-Based Chemotherapy in Patients with Advanced Neuroendocrine Neoplasms – Predictive and Prognostic Markers for Treatment Stratification

BACKGROUND AND AIM: Chemotherapy with streptozocin (STZ) in combination with 5-FU or doxorubicin (Dox) represents a standard of care for patients with metastatic pancreatic neuroendocrine neoplasms (pNEN). However, predictive markers for patient selection are still missing. The aim of this study was...

Descripción completa

Detalles Bibliográficos
Autores principales:	Krug, Sebastian, Boch, Michael, Daniel, Hanna, Nimphius, Wilhelm, Müller, Daniela, Michl, Patrick, Rinke, Anja, Gress, Thomas Matthias
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4668106/ https://www.ncbi.nlm.nih.gov/pubmed/26630134 http://dx.doi.org/10.1371/journal.pone.0143822

Ejemplares similares

Brain metastases in patients with neuroendocrine neoplasms: risk factors and outcome
por: Krug, Sebastian, et al.
Publicado: (2019)

Paraneoplastic brainstem encephalitis in a patient with exceptionally long course of a metastasized neuroendocrine rectum neoplasm
por: Boch, Michael, et al.
Publicado: (2014)

Acromegaly in a patient with a pulmonary neuroendocrine tumor: case report and review of current literature
por: Krug, Sebastian, et al.
Publicado: (2016)

Clinicopathological hallmarks and biomarkers of colorectal neuroendocrine neoplasms
por: Koenig, Alexander, et al.
Publicado: (2017)

Medical Treatment of Gastroenteropancreatic Neuroendocrine Tumors
por: Rinke, Anja, et al.
Publicado: (2012)

Low dose DTIC is effective and safe in pretreated patients with well differentiated neuroendocrine tumors
por: Mueller, Daniela, et al.
Publicado: (2016)

Chemotherapy with 5-fluorouracil, cisplatin and streptozocin for neuroendocrine tumours
por: Turner, N C, et al.
Publicado: (2010)

Leptomeningeal Carcinomatosis: A Clinical Dilemma in Neuroendocrine Neoplasms
por: Apostolidis, Leonidas, et al.
Publicado: (2021)

Interaction between somatostatin analogues and targeted therapies in neuroendocrine tumor cells
por: Krug, Sebastian, et al.
Publicado: (2019)

Correction: Interaction between somatostatin analogues and targeted therapies in neuroendocrine tumor cells
por: Krug, Sebastian, et al.
Publicado: (2020)

Multicenter Analysis of Presacral Neuroendocrine Neoplasms—Clinicopathological Characterization and Treatment Outcomes of a Rare Disease
por: Matrood, Sami, et al.
Publicado: (2021)

CUX1—Transcriptional Master Regulator of Tumor Progression in Pancreatic Neuroendocrine Tumors
por: Krug, Sebastian, et al.
Publicado: (2020)

Streptozocin/5-fluorouracil chemotherapy of pancreatic neuroendocrine tumours in the era of targeted therapy
por: Lahner, Harald, et al.
Publicado: (2021)

Long-term treatment with streptozocin/5-fluorouracil chemotherapy in patients with metastatic pancreatic neuroendocrine tumors: Case series
por: Müller, Christian, et al.
Publicado: (2022)

The Patient’s Point of View: COVID-19 and Neuroendocrine Tumor Disease
por: Krug, Sebastian, et al.
Publicado: (2022)

Finding the Appropriate Therapeutic Strategy in Patients with Neuroendocrine Tumors of the Pancreas: Guideline Recommendations Meet the Clinical Reality
por: Krug, Sebastian, et al.
Publicado: (2021)

Ramucirumab in combination with dacarbazine in patients with progressive well-differentiated metastatic pancreatic neuroendocrine tumors (RamuNET): study protocol for a multicenter single-arm trial
por: Krug, Sebastian, et al.
Publicado: (2021)

Treatment of neuroendocrine tumours with infusional 5-fluorouracil, folinic acid and streptozocin
por: Gonzalez, M A, et al.
Publicado: (2003)

Streptozocin chemotherapy for advanced/metastatic well-differentiated neuroendocrine tumors: an analysis of a multi-center survey in Japan
por: Aoki, Taku, et al.
Publicado: (2014)

Vessel-Sparing Lymphadenectomy Should Be Performed in Small Intestine Neuroendocrine Neoplasms
por: Bartsch, Detlef K., et al.
Publicado: (2022)

A Case of Streptozocin Monotherapy for Unresectable Duodenal Neuroendocrine Tumor G2
por: Miyagawa, Koji, et al.
Publicado: (2019)

Professional Assessment of the Impact of COVID-19 on Handling NET Patients
por: Krug, Sebastian, et al.
Publicado: (2020)

Conventional Transarterial Chemo embolization Using Streptozocin in Patients with Unresectable Neuroendocrine Liver Metastases
por: Fohlen, Audrey, et al.
Publicado: (2023)

Phase I/II study of streptozocin monotherapy in Japanese patients with unresectable or metastatic gastroenteropancreatic neuroendocrine tumors
por: Komoto, Izumi, et al.
Publicado: (2022)

Risk Stratification of Pancreatic Neuroendocrine Neoplasms Based on Clinical, Pathological, and Molecular Characteristics
por: Choi, Jin Ho, et al.
Publicado: (2022)

Emerging concepts in pancreatic cancer medicine: targeting the tumor stroma
por: Neesse, Albrecht, et al.
Publicado: (2013)

Challenges in High-grade Neuroendocrine Neoplasms and Mixed Neuroendocrine/Non-neuroendocrine Neoplasms
por: La Rosa, Stefano
Publicado: (2021)

IGF2BP1 Promotes Proliferation of Neuroendocrine Neoplasms by Post-Transcriptional Enhancement of EZH2
por: Sperling, Florian, et al.
Publicado: (2022)

Perspectives on the diagnostic, predictive and prognostic markers of neuroendocrine neoplasms (Review)
por: Ciobanu, Oana Alexandra, et al.
Publicado: (2021)

Treatment Approaches and Outcome of Patients with Neuroendocrine Neoplasia Grade 3 in German Real-World Clinical Practice
por: Luecke, Simone, et al.
Publicado: (2022)

Neuroendocrine Neoplasms of the Gastrointestinal Tract versus Neuroendocrine Neoplasms of the Gynaecological Tract—Comparison of the Risk Factors and Non-Surgical Treatment Efficacy
por: Lorenz, Anna, et al.
Publicado: (2023)

Are Markers of Systemic Inflammatory Response Useful in the Management of Patients With Neuroendocrine Neoplasms?
por: Giannetta, Elisa, et al.
Publicado: (2021)

Circulating Angiogenic Markers in Gastroenteropancreatic Neuroendocrine Neoplasms: A Systematic Review
por: Sandra, Irina, et al.
Publicado: (2022)

Updates on Diagnostic and Therapeutic Management of Gastrointestinal and Pancreatic NET
por: Krug, Sebastian, et al.
Publicado: (2022)

Biomarkers of Response to Etoposide-Platinum Chemotherapy in Patients with Grade 3 Neuroendocrine Neoplasms
por: Lacombe, Caroline, et al.
Publicado: (2021)

Multicenter, Observational Study of Lanreotide Autogel for the Treatment of Patients with Neuroendocrine Tumors in Routine Clinical Practice in Germany and Austria
por: Rinke, Anja, et al.
Publicado: (2021)

Immunoprofiling in Neuroendocrine Neoplasms Unveil Immunosuppressive Microenvironment
por: Busse, Antonia, et al.
Publicado: (2020)

Targeting HDACs in Pancreatic Neuroendocrine Tumor Models
por: Schmitz, Rosa Lynn, et al.
Publicado: (2021)

Actinin-4 splice variant - a complementary diagnostic and prognostic marker of pancreatic neuroendocrine neoplasms
por: Xu, Xiaojun, et al.
Publicado: (2020)

Histopathology of gastrointestinal neuroendocrine neoplasms
por: Hirabayashi, Kenichi, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_h8k4a9m5a18b463b873o0cvtkd