Middle East respiratory syndrome coronavirus ORF4b protein inhibits type I interferon production through both cytoplasmic and nuclear targets

Middle East respiratory syndrome coronavirus (MERS-CoV) is a novel and highly pathogenic human coronavirus and has quickly spread to other countries in the Middle East, Europe, North Africa and Asia since 2012. Previous studies have shown that MERS-CoV ORF4b antagonizes the early antiviral alpha/bet...

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Detalles Bibliográficos
Autores principales: Yang, Yang, Ye, Fei, Zhu, Na, Wang, Wenling, Deng, Yao, Zhao, Zhengdong, Tan, Wenjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4668369/
https://www.ncbi.nlm.nih.gov/pubmed/26631542
http://dx.doi.org/10.1038/srep17554

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