Preclinical detection of infectivity and disease-specific PrP in blood throughout the incubation period of prion disease

Variant Creutzfeldt-Jakob disease (vCJD) is a fatal neurodegenerative disorder characterised by accumulation of pathological isoforms of the prion protein, PrP. Although cases of clinical vCJD are rare, there is evidence there may be tens of thousands of infectious carriers in the United Kingdom alo...

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Detalles Bibliográficos
Autores principales: Sawyer, Elizabeth B., Edgeworth, Julie Ann, Thomas, Claire, Collinge, John, Jackson, Graham S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4668555/
https://www.ncbi.nlm.nih.gov/pubmed/26631638
http://dx.doi.org/10.1038/srep17742

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4668555/
https://www.ncbi.nlm.nih.gov/pubmed/26631638
http://dx.doi.org/10.1038/srep17742

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