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Re-engineering cellular physiology by rewiring high-level global regulatory genes

Knowledge of global regulatory networks has been exploited to rewire the gene control programmes of the model bacterium Salmonella enterica serovar Typhimurium. The product is an organism with competitive fitness that is superior to that of the wild type but tuneable under specific growth conditions...

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Detalles Bibliográficos
Autores principales: Fitzgerald, Stephen, Dillon, Shane C., Chao, Tzu-Chiao, Wiencko, Heather L., Hokamp, Karsten, Cameron, Andrew D. S., Dorman, Charles J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4668568/
https://www.ncbi.nlm.nih.gov/pubmed/26631971
http://dx.doi.org/10.1038/srep17653