No apparent transmission of transgenic α–synuclein into nigrostriatal dopaminergic neurons in multiple mouse models

BACKGROUND: α–synuclein (α–syn) is the main component of intracytoplasmic inclusions deposited in the brains of patients with Parkinson’s disease (PD) and certain other neurodegenerative disorders. Recent studies have explored the ability of α–syn to propagate between or across neighboring neurons a...

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Detalles Bibliográficos
Autores principales: Sastry, Namratha, Zheng, Wang, Liu, Guoxiang, Wang, Helen, Chen, Xi, Cai, Michael, Contractor, Parth, Sgobio, Carmelo, Sun, Lixin, Xie, Chengsong, Cai, Huaibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4668690/
https://www.ncbi.nlm.nih.gov/pubmed/26635953
http://dx.doi.org/10.1186/s40035-015-0046-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4668690/
https://www.ncbi.nlm.nih.gov/pubmed/26635953
http://dx.doi.org/10.1186/s40035-015-0046-9

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