Cargando…

A Chemical and Enzymatic Approach to Study Site-Specific Sumoylation

A variety of cellular pathways are regulated by protein modifications with ubiquitin-family proteins. SUMO, the Small Ubiquitin-like MOdifier, is covalently attached to lysine on target proteins via a cascade reaction catalyzed by E1, E2, and E3 enzymes. A major barrier to understanding the diverse...

Descripción completa

Detalles Bibliográficos
Autores principales: Albuquerque, Claudio P., Yeung, Eyan, Ma, Shawn, Fu, Ting, Corbett, Kevin D., Zhou, Huilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669148/
https://www.ncbi.nlm.nih.gov/pubmed/26633173
http://dx.doi.org/10.1371/journal.pone.0143810